Wildlife in Mongolia is often in the spotlight at the international level, including two emblematic species, namely the Przewalski’s horse (Equus ferus przewalskii) and Saiga antelope (Saiga tatarica). The issue of wildlife-related diseases, some of which can be traced back to disease incidences in livestock, has been prevalent in Mongolia including the virus known as Peste des Petits Ruminants (PPR) which led to the die-off of 1,000s of Saiga antelope in 2017. With the emergence of new zoonotic diseases along with other anthropogenic activities including the increasing number of domestic animals, the local communities face an increased risk of zoonosis. Many efforts are ongoing to try to minimize these threats, yet knowledge of conservation needs in Mongolia are growing. In addition, wildlife faces pressure from increasing domestic livestock. Collaborating on the Flying Vets project with an initial pilot phase in Mongolia CIC and WOAH in close partnership with Ministry of Environment and Tourism of Mongolia and The Wildlife Conservation Society aim to promote and enhance the ability of local communities in Mongolia to identify, respond to and manage wildlife diseases including the negative consequences for wildlife-domestic livestock interactions through the transmission and spread of diseases including zoonoses, thereby reducing the potential threat posed to public health, food safety as well as wildlife conservation.